Clonal dynamics in the epiphyseal growth plate in Col2-creERT:R26R-Confetti mice at various time points and traced for different periods. PubMed

Contribution of immature Schwann cells to chondrocytes.
Immature Schwann cells were labeled genetically at embryonic day 11.5 (E11.5) with a green fluorescent protein (green color) and some of their progeny (also green) are observed in a cartilage element (visualized by expression of Sox9 chondrocyte marker, red) at the embryonic day E15.5. Nerve fibers are blue (stained by Tuj1). You can also see how intensive innervation around cartilage element is, which includes perichondrium, a thin layer of cells surrounding cartilage elements. PNAS

Tsc1 ablation and elevated mTORC1 activity in growth plate chondrocytes cause resting zone disorganization PubMed

Growth plate chondrocytes in the bones that lacked a SOC were apoptotic in response to high loads biorxiv

Schwann cell precursors generate osteoprogenitor cells and osteocytes in facial region and trunk during murine embryonic development. PubMed

At P5, only cells at the surface of articular cartilage (superficial cells) expressed fluorescent proteins in Prg4CreERT:Confetti mice but after chasing for 1 or 2 month chondrocytes that expressed fluorescent proteins were in the middle and deep zones, which indicated that they were derived from superficial cells. PubMed

Schematic representation of plausible niche components at various skeletal locations. Frontiers